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Astrazena Gout Treatment trial reports positive results
August 13, 2014 12:14 pmVideo
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Drugs giant, Astrazeneca (AZN.L) reported today that the recent phase 3 trial of its latest gout treatment drug, lesinurad, a selective uric acid re-absorption inhibitor (SURI) had hit its primary targets.
however the report did also highlight some possible side effects including respiratory tract infections and back pain though a full assessment of the safety of the drug is ongoing.
“Gout is a serious, chronic and debilitating inflammatory disease. There is a significant unmet need, with 40 to 70 percent of gout patients not reaching target levels of serum uric acid with the current standard of care,” said Briggs Morrison, Executive Vice President, Global Medicines Development and Chief Medical Officer. “We are encouraged by our initial review of the top-line results from the CLEAR1, CLEAR2 and CRYSTAL studies which provide important new information on the efficacy and safety of lesinurad in combination with febuxostat and allopurinol. These data indicate that combination therapy with lesinurad may be a potential treatment option for gout patients.”
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